Who should have a bone density scan (DXA)?

DXA should be performed for:

  • Amenorrhea for more than 6 months and under 45
  • Hyperthyroidism or hyperparathyroidism
  • Malabsorption conditions (including celiac disease)
  • Chronic kidney or liver disease
  • Rheumatoid arthritis
  • Long-term glucocorticoid therapy (e.g. prednisolone ≥7.5 mg/day for 3+ months)
  • Aromatase inhibitor therapy for hormone-sensitive breast cancer

DXA also recommended when:

  • Low or normal body weight (BMI under 20–22)
  • Limited mobility
  • Current smoker
  • More than 2 standard drinks per day
  • Diabetes, malnutrition, or other bone-affecting conditions

Understanding your T-score

T-scoreWhat it means
−1.0 or aboveNormal bone density
−1.0 to −2.5Osteopenia (low bone mass)
−2.5 or belowOsteoporosis
Normal−1.8Osteoporosis

Why −1.8 is a key threshold

Research from the NORA study found that a T-score of −1.8 or below was associated with a meaningful increase in short-term fracture risk in postmenopausal women aged 50+. One-third of all fractures and one-fifth of hip fractures occurred in women aged 50–64.

MHT and bone protection

The Women’s Health Initiative study provides compelling evidence: MHT reduced vertebral and non-vertebral fractures by 34% in a large, diverse group of women, regardless of baseline bone density, BMI, smoking status, history of falls, family history, or calcium intake.

Calcium, vitamin D & lifestyle

Nutrition for bones:

  • Calcium: 1,000–1,200 mg/day through diet
  • Vitamin D: levels above 50 nmol/L; 1,000–2,000 IU/day supplementation commonly recommended
  • Magnesium: cofactor for calcium — nuts, seeds, legumes, dark chocolate
  • Adequate protein for muscle and bone health
  • Vegans: monitor zinc, calcium, vitamin D, and B12

Activity & habits:

  • Weight-bearing exercise and balance training reduce both bone loss and fall risk
  • Limit alcohol to fewer than 2 standard drinks per day
  • Smoking cessation is essential — smoking significantly accelerates bone loss

Sources

  • Davis SR, Taylor S, Hemachandra C, et al. The 2023 Practitioner's Toolkit for Managing Menopause. Climacteric. 2023;26(6):517–536.
  • Women's Health Initiative (WHI) randomized trials of menopausal hormone therapy.
  • NORA (National Osteoporosis Risk Assessment) study.